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  <titleInfo>
    <title>Breast cancer</title>
    <subTitle>innovations in research and management</subTitle>
  </titleInfo>
  <name type="personal">
    <namePart>Veronesi, Umberto</namePart>
    <role>
      <roleTerm type="text">editor.</roleTerm>
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  </name>
  <name type="personal">
    <namePart>Goldhirsch, A. (Aron)</namePart>
    <role>
      <roleTerm type="text">editor.</roleTerm>
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  <name type="personal">
    <namePart>Veronesi, Paolo</namePart>
    <role>
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  </name>
  <name type="personal">
    <namePart>Gentilini, Oreste Davide</namePart>
    <role>
      <roleTerm type="text">editor.</roleTerm>
    </role>
  </name>
  <name type="personal">
    <namePart>Leonardi, Maria Cristina</namePart>
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      <roleTerm type="text">editor.</roleTerm>
    </role>
  </name>
  <typeOfResource>text</typeOfResource>
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    <place>
      <placeTerm type="text">Cham, Switzerland</placeTerm>
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    <publisher>Springer</publisher>
    <dateIssued>2017</dateIssued>
    <dateIssued>2017</dateIssued>
    <issuance>monographic</issuance>
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  <language>
    <languageTerm authority="iso639-2b" type="code">eng</languageTerm>
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    <extent>1 recurso en línea (xiv, 928 páginas) : ilustraciones (some color)</extent>
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  <abstract>Este libro proporciona al lector información actualizada sobre avances importantes en la comprensión del cáncer de mama y enfoques innovadores para su manejo. Las perspectivas actuales y emergentes sobre genética, biología y prevención se analizan primero en profundidad, y las secciones individuales se dedican a patología, imagenología, cirugía oncológica, cirugía plástica y reconstructiva, oncología médica y radioterapia. En cada caso, la atención se centra en el progreso más reciente y / o las terapias y técnicas de vanguardia. Otros temas para recibir una consideración detallada incluyen condiciones particulares que requieren enfoques multidisciplinarios, la investigación de nuevos fármacos y agentes inmunológicos, aspectos de estilo de vida y psicológicos, y bioestadística e informática. El libro ser una excelente referencia para profesionales, pasantes y residentes en oncología médica, cirugía oncológica, radioterapia, patología y genética humana, investigadores y estudiantes de medicina avanzados.</abstract>
  <tableOfContents>Scellaneous Approaches -- Lifestyle and breast cancer -- Psychological support -- HIFU and radiofrequency as alternatives to surgery -- Hyperthermia with RT and with systemic therapies -- Electro-chemotherapy -- Circulating miRNA in early diagnosis -- Relevance  of stem cells -- Part XII Biostatistics and Bioinformatics -- Subgroup analyses and information from clinical trials on  breast cancer -- The methodology of meta analyses and its potential contribution to patient care -- Modern biostatistics  for accelerated  data acquisition for new drugs -- Bioinformatics for clinical use in breast cancer -- Efficacy endpoints in breast cancer studies and definitive  implant replacement -- Breast reconstruction with pedicled flaps -- Breast reconstruction with free flaps -- Contralateral breast management -- Fat grafting in breast reconstruction -- Breast reconstruction with biological and nonbiological  meshes -- How to manage complications in breast reconstruction -- Part VII Medical Oncology -- Adjuvant systemic therapies by subtypes: guidelines -- Primary systemic therapies: guidelines -- Treatment of advanced disease: guidelines -- Endocrine therapies in the adjuvant and advanced disease settings -- Chemotherapy regimens in the adjuvant and advanced disease settings -- Anti-HER2 therapies in the adjuvant and advanced disease settings -- Systemic therapy with bisphosphonates and anti-RANK-L agents -- Systemic treatment for specific medical situations -- Part VIII Radiotherapy -- Conceptual basis and principles of radiation oncology -- Whole breast radiation following breast-conserving surgery in invasive cancer -- Whole breast radiation following breast-conserving surgery in noninvasive cancer -- Post-mastectomy radiotherapy -- Integration of radiotherapy with systemic therapies -- Partial breast irradiation -- Intraoperative radiotherapy ELIOT -- Radiotherapy for metastatic lesions -- Part IX Special Conditions Requiring Multidisciplinary Approaches -- Emergencies in breast cancer -- Breast cancer during pregnancy -- Fertility issues in patients with newly diagnosed breast cancer -- Sexual functions and breast cancer -- Male breast cancer -- Inflammatory  breast cancer -- Treatment of CNS involvement -- Treatment of skeletal disease -- Follow-up of patients with breast cancer -- Part X Investigating New Drugs and Immunological Agents in Breast Cancer -- Targeting immune-checkpoint -- Targeting PIK3CA/AKT/mTOR -- Targeting genome instability and DNA repair -- Targeting CDK4/6 pathway -- Targeting FGFR pathway -- Integrating next generation sequencing data in trial design -- Part XI Investigational and Mi.</tableOfContents>
  <note type="statement of responsibility">Umberto Veronesi, Aron Goldhirsch, editors-in-chief ; Paolo Veronesi, Oreste Davide Gentilini, Maria Cristina Leonardi, editors.</note>
  <note>Incluye referencias bibliográficas e índice.</note>
  <subject authority="lcsh">
    <topic>Pecho</topic>
    <topic>Cancer</topic>
  </subject>
  <subject authority="lcsh">
    <topic>Pecho</topic>
    <topic>Cancer</topic>
    <topic>Diagnóstico</topic>
  </subject>
  <subject authority="lcsh">
    <topic>Pecho</topic>
    <topic>Cancer</topic>
    <topic>Tratamiento</topic>
  </subject>
  <classification authority="ddc" edition="23">616.99449</classification>
  <identifier type="isbn">9783319488486</identifier>
  <identifier type="isbn">9783319488462</identifier>
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    <recordCreationDate encoding="marc">171114</recordCreationDate>
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