09108nam a2200421 a 4500 20260513213927.0 m d cr cnu---uuuuu 171114s2017 s 000 0 eng d 9783319488486 (eBook) 9783319488462 (Hardback) CO-CtgCURN spa coctgcurn 616.99449 23 Breast cancer [electronic resource] : innovations in research and management / Umberto Veronesi, Aron Goldhirsch, editors-in-chief ; Paolo Veronesi, Oreste Davide Gentilini, Maria Cristina Leonardi, editors. Cham, Switzerland : : : Springer,,, 2017. 2017. 1 recurso en línea (xiv, 928 páginas) : ilustraciones (some color) texto txt rdacontent computador c rdamedia recurso en línea cr rdacarrier Incluye referencias bibliográficas e índice. Scellaneous Approaches -- Lifestyle and breast cancer -- Psychological support -- HIFU and radiofrequency as alternatives to surgery -- Hyperthermia with RT and with systemic therapies -- Electro-chemotherapy -- Circulating miRNA in early diagnosis -- Relevance  of stem cells -- Part XII Biostatistics and Bioinformatics -- Subgroup analyses and information from clinical trials on  breast cancer -- The methodology of meta analyses and its potential contribution to patient care -- Modern biostatistics  for accelerated  data acquisition for new drugs -- Bioinformatics for clinical use in breast cancer -- Efficacy endpoints in breast cancer studies and definitive  implant replacement -- Breast reconstruction with pedicled flaps -- Breast reconstruction with free flaps -- Contralateral breast management -- Fat grafting in breast reconstruction -- Breast reconstruction with biological and nonbiological  meshes -- How to manage complications in breast reconstruction -- Part VII Medical Oncology -- Adjuvant systemic therapies by subtypes: guidelines -- Primary systemic therapies: guidelines -- Treatment of advanced disease: guidelines -- Endocrine therapies in the adjuvant and advanced disease settings -- Chemotherapy regimens in the adjuvant and advanced disease settings -- Anti-HER2 therapies in the adjuvant and advanced disease settings -- Systemic therapy with bisphosphonates and anti-RANK-L agents -- Systemic treatment for specific medical situations -- Part VIII Radiotherapy -- Conceptual basis and principles of radiation oncology -- Whole breast radiation following breast-conserving surgery in invasive cancer -- Whole breast radiation following breast-conserving surgery in noninvasive cancer -- Post-mastectomy radiotherapy -- Integration of radiotherapy with systemic therapies -- Partial breast irradiation -- Intraoperative radiotherapy ELIOT -- Radiotherapy for metastatic lesions -- Part IX Special Conditions Requiring Multidisciplinary Approaches -- Emergencies in breast cancer -- Breast cancer during pregnancy -- Fertility issues in patients with newly diagnosed breast cancer -- Sexual functions and breast cancer -- Male breast cancer -- Inflammatory  breast cancer -- Treatment of CNS involvement -- Treatment of skeletal disease -- Follow-up of patients with breast cancer -- Part X Investigating New Drugs and Immunological Agents in Breast Cancer -- Targeting immune-checkpoint -- Targeting PIK3CA/AKT/mTOR -- Targeting genome instability and DNA repair -- Targeting CDK4/6 pathway -- Targeting FGFR pathway -- Integrating next generation sequencing data in trial design -- Part XI Investigational and Mi. Este libro proporciona al lector información actualizada sobre avances importantes en la comprensión del cáncer de mama y enfoques innovadores para su manejo. Las perspectivas actuales y emergentes sobre genética, biología y prevención se analizan primero en profundidad, y las secciones individuales se dedican a patología, imagenología, cirugía oncológica, cirugía plástica y reconstructiva, oncología médica y radioterapia. En cada caso, la atención se centra en el progreso más reciente y / o las terapias y técnicas de vanguardia. Otros temas para recibir una consideración detallada incluyen condiciones particulares que requieren enfoques multidisciplinarios, la investigación de nuevos fármacos y agentes inmunológicos, aspectos de estilo de vida y psicológicos, y bioestadística e informática. El libro ser una excelente referencia para profesionales, pasantes y residentes en oncología médica, cirugía oncológica, radioterapia, patología y genética humana, investigadores y estudiantes de medicina avanzados. Pecho Cancer. Pecho Cancer Diagnóstico. Pecho Cancer Tratamiento. Veronesi, Umberto, editor. Goldhirsch, A. (Aron), editor. Veronesi, Paolo, editor. Gentilini, Oreste Davide, editor. Leonardi, Maria Cristina, editor. MHE MHE CF 616.99449 B828 https://unicurn.sharepoint.com/:b:/s/biblioteca/EaZnuNQTNcpAm88PcsbQmzgBFAyFlr3HVtkXk_R36l0ixg?e=yY91jy <img src="/screens/gifs/go4.gif" alt="Go button" border="0" width="21" height="21" hspace="7" align=middle"> Vea este libro electrónico Scellaneous Approaches -- Lifestyle and breast cancer -- Psychological support -- HIFU and radiofrequency as alternatives to surgery -- Hyperthermia with RT and with systemic therapies -- Electro-chemotherapy -- Circulating miRNA in early diagnosis -- Relevance of stem cells -- Part XII Biostatistics and Bioinformatics -- Subgroup analyses and information from clinical trials on breast cancer -- The methodology of meta analyses and its potential contribution to patient care -- Modern biostatistics for accelerated data acquisition for new drugs -- Bioinformatics for clinical use in breast cancer -- Efficacy endpoints in breast cancer studies and definitive implant replacement -- Breast reconstruction with pedicled flaps -- Breast reconstruction with free flaps -- Contralateral breast management -- Fat grafting in breast reconstruction -- Breast reconstruction with biological and nonbiological meshes -- How to manage complications in breast reconstruction -- Part VII Medical Oncology -- Adjuvant systemic therapies by subtypes: guidelines -- Primary systemic therapies: guidelines -- Treatment of advanced disease: guidelines -- Endocrine therapies in the adjuvant and advanced disease settings -- Chemotherapy regimens in the adjuvant and advanced disease settings -- Anti-HER2 therapies in the adjuvant and advanced disease settings -- Systemic therapy with bisphosphonates and anti-RANK-L agents -- Systemic treatment for specific medical situations -- Part VIII Radiotherapy -- Conceptual basis and principles of radiation oncology -- Whole breast radiation following breast-conserving surgery in invasive cancer -- Whole breast radiation following breast-conserving surgery in noninvasive cancer -- Post-mastectomy radiotherapy -- Integration of radiotherapy with systemic therapies -- Partial breast irradiation -- Intraoperative radiotherapy ELIOT -- Radiotherapy for metastatic lesions -- Part IX Special Conditions Requiring Multidisciplinary Approaches -- Emergencies in breast cancer -- Breast cancer during pregnancy -- Fertility issues in patients with newly diagnosed breast cancer -- Sexual functions and breast cancer -- Male breast cancer -- Inflammatory breast cancer -- Treatment of CNS involvement -- Treatment of skeletal disease -- Follow-up of patients with breast cancer -- Part X Investigating New Drugs and Immunological Agents in Breast Cancer -- Targeting immune-checkpoint -- Targeting PIK3CA/AKT/mTOR -- Targeting genome instability and DNA repair -- Targeting CDK4/6 pathway -- Targeting FGFR pathway -- Integrating next generation sequencing data in trial design -- Part XI Investigational and Mi This book provides the reader with up-to-date information on important advances in the understanding of breast cancer and innovative approaches to its management. Current and emerging perspectives on genetics, biology, and prevention are first discussed in depth, and individual sections are then devoted to pathology, imaging, oncological surgery, plastic and reconstructive surgery, medical oncology, and radiotherapy. In each case the focus is on the most recent progress and/or state of the art therapies and techniques. Further topics to receive detailed consideration include particular conditions requiring multidisciplinary approaches, the investigation of new drugs and immunological agents, lifestyle and psychological aspects, and biostatistics and informatics. The book will be an excellent reference for practitioners, interns and residents in medical oncology, oncologic surgery, radiotherapy, pathology, and human genetics, researchers, and advanced medical students Includes bibliographical references CF 616.99449 B828 ddc 7918 7918 0 0 ddc 0 616_994490000000000_B828 0 CF MHE MHE CF 2025-03-29 0 616.99449 B828 2025-03-29 17:09:40 CF 2025-03-29